Economic Assessment in Resource-Constrained Systems: Individual-Level Simulation Model in Wet Age-Related Macular Degeneration and Diabetic Macular Oedema.
Danying LiVladislav BerdunovRobin HamiltonYaneth Gil RojasChristian BührerOliver CoxRoelien PostemaMarloes BagijnPublished in: Ophthalmology and therapy (2024)
Accounting for resource constraints in health economic evaluation is crucial. Emerging therapies that are more durable and require less frequent clinic visits can reduce treatment delays, leading to improved QALY outcomes and reduced burden on healthcare systems. Faricimab reduced the number of delayed injections, leading to improved QALY outcomes for patients in a healthcare system with resource constraints. Faricimab is cost-saving when compared with aflibercept and cost-effective when compared with ranibizumab biosimilar.
Keyphrases
- age related macular degeneration
- healthcare
- end stage renal disease
- newly diagnosed
- chronic kidney disease
- ejection fraction
- public health
- diabetic retinopathy
- primary care
- health information
- optical coherence tomography
- patient reported outcomes
- social media
- combination therapy
- climate change
- risk assessment
- ultrasound guided
- smoking cessation