Association Between the A118G Polymorphism of the OPRM1 Gene and Suicidal Depression in a Large Cohort of Outpatients with Depression.

Benedicte NobileEmilie OlieNicolas RamozJonathan DuboisSebastien GuillaumePhilip GorwoodPhilippe Courtet

Published in: Neuropsychiatric disease and treatment (2021)

Outpatients with depression harbouring the A allele are at higher risk of SI (and possibly SB) than those carrying the G allele. More studies are needed to better understand the link between this polymorphism and SB.

Keyphrases

depressive symptoms
sleep quality
genome wide
copy number
physical activity
transcription factor
dna methylation