Immunomodulatory effects of renin-angiotensin system inhibitors on T lymphocytes in mice with colorectal liver metastases.

Dora Lucia Vallejo Ardila Katrina A Walsh Theodora Fifis Rita Paolini Georgios Kastrappis Christopher Christophi Marcos Vinicius Perini

Published in: Journal for immunotherapy of cancer (2021)

Captopril treatment modulates the immune response by increasing the infiltration and altering the phenotypical composition of T lymphocytes and may be a contributing mechanism for tumor control.

Keyphrases

liver metastases
immune response
dendritic cells
type diabetes
toll like receptor
combination therapy
inflammatory response
insulin resistance
smoking cessation