Effect of metformin on left ventricular mass and functional parameters in non-diabetic patients: a meta-analysis of randomized clinical trials.

Ahmed M Kamel Nirmeen A Sabry Samar F Farid

Published in: BMC cardiovascular disorders (2022)

Results suggest a favorable effect for metformin on LVMI and LVEF in patients with or without pre-existing CVD. Additional trials are needed to address the long-term effect of metformin. Registration The study was registered on the PROSPERO database with the registration number CRD42021239368 ( https://www.crd.york.ac.uk/prospero ).

Keyphrases

left ventricular
heart failure
emergency department
clinical trial
hypertrophic cardiomyopathy
aortic stenosis
cardiac resynchronization therapy
adverse drug
acute coronary syndrome
aortic valve
electronic health record