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Clinical outcomes of advanced NSCLC patients with different EGFR exon 19 deletion subtypes treated with first-line tyrosine kinase inhibitors: A single-center ambispective cohort study.

Yangchun GuJinyu YuHaifeng HuHua ZhangBaoshan CaoLi Liang
Published in: Thoracic cancer (2023)
Our study revealed potential differences in TKI efficacy, resistance mechanism, and prognosis of various EGFR ex19del subtypes in NSCLC, underscoring the need for precise selection of first-line therapy.
Keyphrases
  • small cell lung cancer
  • advanced non small cell lung cancer
  • epidermal growth factor receptor
  • tyrosine kinase
  • brain metastases
  • chronic myeloid leukemia
  • single cell
  • stem cells
  • risk assessment