SRY-negative 46,XX testicular/ovotesticular DSD: Long-term outcomes and early blockade of gonadotropic axis.

Sophie LambertMatthieu PeycelonDinane Samara-BoustaniCapucine HyonLaurence DumeigeMichel PeuchmaurElodie FiotJuliane LégerDominique SimonAnnabel Paye-JaouenJérome BouligandJean-Pierre SiffroiJean-Claude CarelKen McElreaveyAlaa El GhoneimiCécile BrachetClaire BouvattierLaetitia Martinerie

Published in: Clinical endocrinology (2020)

This study presents a population of patients with 46,XX SRY-negative T/OTDSD. Early blockade of gonadotropic axis appears efficient to reduce and avoid further androgenization in patients raised as girls.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
patient reported outcomes