Automated immunohistochemistry of intra-epidermal nerve fibres in skin biopsies: A proof-of-concept study.
Jamie BurgessAnne MarshallLeandros RapteasJ Hamill KevinAndrew MarshallRayaz Ahmed MalikBernhard FrankUazman AlamPublished in: Journal of the peripheral nervous system : JPNS (2024)
Automated immunohistochemistry provides high-throughput reliable and reproducible intra-epidermal nerve fibre quantification. This method, although currently proof-of-concept, for research use only, may be more widely deployed in histopathology laboratories to increase the adoption of IENFD assessment for the diagnosis of peripheral neuropathies.