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Automated immunohistochemistry of intra-epidermal nerve fibres in skin biopsies: A proof-of-concept study.

Jamie BurgessAnne MarshallLeandros RapteasJ Hamill KevinAndrew MarshallRayaz Ahmed MalikBernhard FrankUazman Alam
Published in: Journal of the peripheral nervous system : JPNS (2024)
Automated immunohistochemistry provides high-throughput reliable and reproducible intra-epidermal nerve fibre quantification. This method, although currently proof-of-concept, for research use only, may be more widely deployed in histopathology laboratories to increase the adoption of IENFD assessment for the diagnosis of peripheral neuropathies.
Keyphrases
  • high throughput
  • wound healing
  • peripheral nerve
  • deep learning
  • single cell
  • machine learning
  • ultrasound guided