Overexpression of CFL1 in gastric cancer and the effects of its silencing by siRNA with a nanoparticle delivery system in the gastric cancer cell line.

Seyedeh Saideh DaryabariMarziyeh FathiMajid MahdaviYaghoub MoaddabMohammad Ali Hosseinpour FeiziBehrouz ShokoohiReza Safaralizadeh

Published in: Journal of cellular physiology (2020)

Our results demonstrated that CFL1 downregulation in AGS cells can interdict cell migration. Finally, our outcomes propose that CFL1 can function as an oncogenic gene in gastric cancer and would be considered as a potential purpose of gene therapy for gastric cancer treatment.

Keyphrases

cell migration
induced apoptosis
cell proliferation
copy number
genome wide
transcription factor
genome wide identification
cell cycle arrest
cancer therapy
skeletal muscle
risk assessment
adipose tissue
cell death
climate change
insulin resistance
genome wide analysis
weight loss