Enhanced liver fibrosis score stratifies hepatocellular carcinoma risk in patients with hepatitis B surface antigen seroclearance.
Lung-Yi MakKa-Shing CheungRex Wan-Hin HuiDanny Ka-Ho WongJames FungMan-Fung YuenWai Kay SetoPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2022)
In this prospective study involving 337 chronic hepatitis B patients who achieved spontaneous HBsAg seroclearance (SC), serum Enhanced Liver Fibrosis (ELF) before SC was associated with hepatocellular carcinoma (HCC) (hazard ratio 2.588), and ELF <10.8 was associated with >97% reduction in risk of HCC development in patients with ageSC≥50 (n = 190).
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