Clinical and molecular characterization of early-onset colorectal cancer.

Alexandra N WillauerYusha LiuAllan A L PereiraMichael LamJeffrey S MorrisKanwal P S RaghavVan K MorrisDavid MenterRussell BroaddusFunda Meric-BernstamAndrea Hayes-JordanWinston HuhMichael J OvermanScott KopetzJonathan M Loree

Published in: Cancer (2019)

Early-onset CRC is not only distinct from traditional CRC: special consideration should be given to and further investigations should be performed for both very young patients with CRC (18-29 years) and those with predisposing conditions. The etiology of the high rate of CMS1 in patients younger than 40 years deserves further exploration.

Keyphrases

early onset
late onset
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
prognostic factors