Comparative evaluation of efficacy and safety of automated versus manual red cell exchange in sickle cell disease: A systematic review and meta-analysis.

Somnath MukherjeeAnsuman SahuGopal Krushna RayRituparna MaitiSatya Prakash

Published in: Vox sanguinis (2022)

This meta-analysis did not reveal any significant benefit of aRBX in reducing HbS percentage and attenuating the serum ferritin level when compared with MET. There was also no significant increased risk of adverse events detected in association with aRBX.

Keyphrases

sickle cell disease
systematic review
single cell
high throughput
meta analyses
machine learning
cell therapy
deep learning
tyrosine kinase
case control
gene expression
stem cells