Delivery of antisense oligonucleotides for splice-correction of androgen receptor pre-mRNA in castration-resistant prostate cancer models using cell-penetrating peptides.
Maria V Luna-VelezOmar Paulino da Silva FilhoGerald W VerhaeghOnno van HooijNajoua El BoujnouniRoland BrockJack A SchalkenPublished in: The Prostate (2022)
This proof-of-principle study constitutes the basis for further development of CPP-mediated delivery of AONs for targeted therapy in prostate cancer.