Population pharmacokinetic model of free and total ropivacaine after transversus abdominis plane nerve block in patients undergoing liver resection.
Edouard OllierFabrice HeritierCaroline BonnetSophie HodinBrigitte BeauchesneSerge MolliexXavier DelavennePublished in: British journal of clinical pharmacology (2015)
Although large liver resections were associated with lower free ropivacaine clearance, the ropivacaine pharmacokinetic profile remained within the safe range after this type of surgery.