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The role of immunotherapy plus chemotherapy versus chemotherapy alone as first-line treatment for advanced non-small cell lung cancer: an updated systematic review and meta-analysis of randomized controlled trials.

Basel AbdelazeemKirellos Said AbbasFatma LabiebAbdul Karim AridaNahla Ahmed El-ShahatJoseph ShehataEmad KandahBilal MalikMaxwell Oluwole AkanbiAbdul RafaeAhsan WahabHamid Ehsan
Published in: Expert review of anticancer therapy (2022)
The combination of immunotherapy and chemotherapy as first-line treatment for advanced NSCLC significantly improved PFS and OS compared to chemotherapy alone without a significant increase in the overall TRAEs.
Keyphrases
  • advanced non small cell lung cancer
  • locally advanced
  • epidermal growth factor receptor
  • squamous cell carcinoma
  • rectal cancer
  • chemotherapy induced