Local application of curcumin-loaded nanoparticles as an adjunct to scaling and root planing in periodontitis: Randomized, placebo-controlled, double-blind split-mouth clinical trial.
Cindy Grace Pérez-PachecoNatalie Ap Rodrigues FernandesFernando Lucas PrimoAntonio Claudio TedescoEmily BellileBelen Retamal-ValdesMagda FeresMorgana Rodrigues Guimarães-StabiliCarlos Rossa JuniorPublished in: Clinical oral investigations (2020)
Our results showed that a single local application of curcumin-loaded nanoparticles associated with nonsurgical periodontal therapy did not improve clinical outcomes. Hence, our findings do not support the use of curcumin as an adjunct to nonsurgical periodontal therapy.