Extensive ischemic colitis-like colonic lesions in eosinophilic granulomatosis with polyangiitis.

Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare, immune-mediated, multisystemic disorder belonging to the group of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides. Gastrointestinal (GI) symptoms are relatively common in patients with EGPA, reportedly occurring in about 22.3% of cases. Vasculitic necrotizing lesions normally occur in the intestinal tract, and in the present case, the colonic lesions were remarkably severe and extensive. Pulse steroid therapy combined with cyclophosphamide improved the patient's condition without any serious complications, such as intestinal perforation.