Recent Advances in Plant-Mediated Zinc Oxide Nanoparticles with Their Significant Biomedical Properties.
Muhanad AlhujailySalim AlbukhatyMohammad YusufMustafa K A MohammedGhassan M SulaimanHassan Al-KaragolyAmal Ahmed AlyamaniJawaher AlbaqamiFaizah A AlMalkiPublished in: Bioengineering (Basel, Switzerland) (2022)
Compared to traditional physical and chemical approaches, nanobiotechnology and plant-based green synthesis procedures offer significant advantages, as well as having a greater range of medical and biotechnological applications. Nanoparticles of zinc oxide (ZnO NPs) have recently been recognized as a promising option for many industries, including optics, electrics, packaged foods, and medicine, due to their biocompatibility, low cytotoxicity, and cost-effectiveness. Several studies have shown that zinc ions are important in triggering cell apoptosis by promoting the generation of reactive oxygen species (ROSs) and releasing zinc ions (Zn 2+ ), which are toxic to cells. The toxic nature of the chemicals used in the synthesis of ZnO nanoparticles limits their clinical utility. An overview of recent developments in green ZnO NP synthesis is presented in this review, emphasizing plant parts as reducing agents and their medical applications, including their antimicrobial, anticancer, antioxidant, and anti-inflammatory properties, as well as key mechanisms of action for these applications to facilitate further research on the biomedical fields in the future.
Keyphrases
- oxide nanoparticles
- quantum dots
- anti inflammatory
- reactive oxygen species
- room temperature
- healthcare
- induced apoptosis
- reduced graphene oxide
- oxidative stress
- staphylococcus aureus
- mental health
- heavy metals
- cell cycle arrest
- cell wall
- cell death
- endoplasmic reticulum stress
- current status
- aqueous solution
- risk assessment
- water soluble
- light emitting
- plant growth