Understanding the role of mesenchymal stem cells in urinary bladder regeneration-a preclinical study on a porcine model.
Marta PokrywczynskaArkadiusz JundzillMarta RasmusJan AdamowiczDaria BalcerczykMonika BuhlKarolina WardaLukasz BuchholzMaciej GagatDariusz GrzankaTomasz DrewaPublished in: Stem cell research & therapy (2018)
The data demonstrate that ADSCs support regeneration of large defects of the urinary bladder wall but the process is incomplete in the central graft region. Stem cells enhance urinary bladder regeneration indirectly through paracrine effect.