Modified Histopathological Grading Optimizes Prediction of Survival Outcomes in Small Intestinal Neuroendocrine Tumours.
Kosmas DaskalakisMarina TsoliGöran WallinAngelika KogutRaj SrirajaskanthanChristopher HarlowGeorgios GiovosMartin O WeickertBeata Kos-KudlaGregory KaltsasPublished in: The Journal of clinical endocrinology and metabolism (2024)
Ki-67 proliferation index was a strong and independent predictor of OS and EFS. A modified histopathological grading system applying Ki-67 cut-offs of 5 and 10% could be superior to predict differences in SI-NET patient survival outcomes.