Tofacitinib enhances remyelination and improves myelin integrity in cuprizone-induced mice.
Caner GunaydinMehmet Emin OngerBahattin AvciAyhan BozkurtMurat TerziSüleyman Sırrı BilgePublished in: Immunopharmacology and immunotoxicology (2021)
Our study highlights JAK/STAT inhibition provides beneficial effects on remyelination via inhibition of inflammatory cascade.