Hierarchical contribution of individual lifestyle factors and their interactions on adenomatous and serrated polyp risk.
Jihee KimKirti NathKurt SchmidlinHelen SchaufelbergerChristiana QuattropaniSimone VanniniSandro MossiMiriam ThumshirnMichael ManzLev LitichevskiyJiaxin FanOxana Dmitrieva-PosoccoMingyao LiMaayan LevyPrimo SchärMarcel ZwahlenChristoph A ThaissKaspar TruningerPublished in: Journal of gastroenterology (2023)
Individual risk factors and their interactions for polyp formation along the adenomatous and serrated pathways are strongly heterogeneous. Our findings may facilitate tailored lifestyle recommendations and contribute to a better understanding of how risk factor combinations impact colorectal carcinogenesis.