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The SIRT1/Nrf2 signaling pathway mediates the anti-pulmonary fibrosis effect of liquiritigenin.

Qingzhong HuaLu Ren
Published in: Chinese medicine (2024)
Our findings imply that targeting myofibroblast differentiation via the SIRT1/Nrf2 signaling pathway may constitute a pivotal strategy for liquiritigenin-based therapy against pulmonary fibrosis.
Keyphrases
  • pulmonary fibrosis
  • signaling pathway
  • oxidative stress
  • pi k akt
  • induced apoptosis
  • ischemia reperfusion injury
  • epithelial mesenchymal transition
  • cancer therapy
  • cell proliferation