Brainstem astrocytoma as a neuro-Behçet's disease mimic.
Julia ManassonJonathan HowardJohannes NowatzkyPublished in: BMJ case reports (2018)
A 58-year-old man with a history of recurrent aphthous ulcers since childhood was admitted to the hospital with acute neurological decline characterised by loss of motor dexterity, dysarthria, dysphagia and unsteady gait. MRI brain was significant for symmetrical hyperintense T2 fluid attenuated inversion recovery (FLAIR) in the corticospinal tracts, including parts of the pons and the mesodiencephalic junction. Though initial concern was for neuro-Behçet's disease, brain biopsy ultimately revealed a diagnosis of astrocytoma. This report demonstrates a mimic of neuro-Behçet's disease and the importance of confirming the correct diagnosis prior to initiating therapy.
Keyphrases
- white matter
- resting state
- healthcare
- magnetic resonance imaging
- liver failure
- contrast enhanced
- stem cells
- cerebral ischemia
- multiple sclerosis
- functional connectivity
- bone marrow
- brain injury
- blood brain barrier
- transcranial magnetic stimulation
- high frequency
- early life
- replacement therapy
- extracorporeal membrane oxygenation
- aortic dissection