Neurologic syndromes related to anti-GAD65: Clinical and serologic response to treatment.
Amaia Muñoz-LopetegiMarienke A A M de BruijnSanae BoukhrissiAnna E M BastiaansenMariska M P NagtzaamEsther S P HulsenboomAgnita J W BoonRinze Frederik NeuteboomJuna M de VriesPeter A E Sillevis SmittMarco W J SchreursMaarten J TitulaerPublished in: Neurology(R) neuroimmunology & neuroinflammation (2020)
Most patients with high anti-GAD65 concentrations (>10,000 IU/mL) showed some improvement after immunotherapy, unfortunately without complete recovery. Serum antibody concentrations' course might be useful to monitor response. In patients with low anti-GAD65 concentrations, especially in those without typical clinical phenotypes, diagnostic alternatives are more likely.
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