LncRNA LINC00942 promotes chemoresistance in gastric cancer by suppressing MSI2 degradation to enhance c-Myc mRNA stability.

Yiran ZhuBingluo ZhouXinyang HuShilong YingQiyin ZhouWenxia XuLifeng FengTianlun HouXian WangLiyuan ZhuHongchuan Jin

Published in: Clinical and translational medicine (2022)

These results uncover a chemoresistant accelerating function of LNC942 in GC, and disrupting the LNC942-MSI2-c-Myc axis could be a novel therapeutic strategy for GC patients undergoing chemoresistance.

Keyphrases

patients undergoing
long non coding rna
long noncoding rna
gas chromatography
cell proliferation
cancer stem cells
tandem mass spectrometry