A genetic variant in CDKN2A/B gene is associated with the increased risk of breast cancer.
Soodabeh ShahidSalesMehraneh MehramizFaezeh GhasemiAmir AledavoodMehri ShamsiSeyed Mahdi HassanianMajid Ghayour-MobarhanSoodabeh ShahidsalesPublished in: Journal of clinical laboratory analysis (2017)
We demonstrated that patients carrying the TT genotype for CDKN2A/B rs10811661 polymorphism had the increased risk of breast cancer susceptibility. However, further investigations are warranted in a larger and prospective setting to explore the value of this marker as a risk stratification marker in breast cancer.