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PyIR: a scalable wrapper for processing billions of immunoglobulin and T cell receptor sequences using IgBLAST.

Cinque SotoJessica A FinnJordan R WillisSamuel B DayRobert S SinkovitsTaylor JonesSamuel SchmitzJens MeilerAndre BranchizioJames E Crowe
Published in: BMC bioinformatics (2020)
PyIR offers improved processing speed over multithreaded IgBLAST (version 1.14) when spawning more than 16 processes on a single computer system. Its customizable filtering and data encapsulation allow it to be adapted to a wide range of computing environments. The API allows for IgBLAST to be used in customized bioinformatics workflows.
Keyphrases
  • electronic health record
  • deep learning
  • big data
  • psychometric properties
  • machine learning