Sorafenib attenuates liver fibrosis by triggering hepatic stellate cell ferroptosis via HIF-1α/SLC7A11 pathway.
Siyu YuanCan WeiGuofang LiuLijun ZhangJiahao LiLingling LiShiyi CaiLing FangPublished in: Cell proliferation (2021)
Sorafenib triggers HSC ferroptosis via HIF-1α/SLC7A11 signalling, which in turn attenuates liver injury and fibrosis.