Predictors of Sentinel Lymph Node Metastasis in Patients with Thin Melanoma: An International Multi-institutional Collaboration.

Richard J B WalkerNicole J Look HongMarc D S MoncrieffAlexander C J van AkkooiEvan JostCarolyn NessimWinan J van HoudtEmma H A StahlieChanhee SeoMay Lynn QuanJ Gregory McKinnonFrances C WrightMichail N Mavros

Published in: Annals of surgical oncology (2022)

Our international multi-institutional data confirm that Breslow thickness and mitotic rate independently predict SLNB positivity in patients with T1 melanoma. Even within this highly selected population, the number needed to diagnose is 13:1 (7.8%), indicating that more work is required to identify additional predictors of sentinel node positivity.

Keyphrases

sentinel lymph node
lymph node
early stage
neoadjuvant chemotherapy
skin cancer
cell cycle
electronic health record
squamous cell carcinoma
cell proliferation
rectal cancer