Premorbid body weight predicts weight loss in both anorexia nervosa and atypical anorexia nervosa: Further support for a single underlying disorder.
Johannes HebebrandJochen SeitzManuel FöckerHanna Preuss-van ViersenMichael HussKatharina BührenBrigitte DahmenKatja BeckerLinda WeberChristoph U CorrellCharlotte JaiteKarin Maria EgbertsMarcel RomanosStefan EhrlichMaria SeidelVeit RoessnerChristian FleischhakerEva MöhlerFreia HahnMichael KaessTanja LegenbauerDaniela HagmannTobias J RennerUlrike M E SchulzeUlf ThiemannIda WessingGisela AntonyKatharina BührenAbigail MatthewsTriinu PetersPublished in: The International journal of eating disorders (2024)
Because body weights of patients with AN must drop below the 5th BMI-centile per DSM-5, they will inherently require greater weight loss than their counterparts with atypical AN of the same sex, age, height and premorbid weight. Indeed, patients with atypical AN had a 5.6 kg lower weight loss after controlling for these variables. In comparison to the reference population, we found a lower and higher mean premorbid weight in patients with AN and atypical AN, respectively. Considering previous psychological and medical comparisons showing little differences between AN and atypical AN, we view a single disorder as the most parsimonious explanation. Etiological models need to particularly account for the strong relationship between weight loss and premorbid body weight.