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LncRNA Profiling Reveals That the Deregulation of H19, WT1-AS, TCL6, and LEF1-AS1 Is Associated with Higher-Risk Myelodysplastic Syndrome.

Katarina SzikszaiZdenek KrejcikJiří KlémaNikoleta LoudovaAndrea HrustincovaMonika BelickovaMonika HrubaJitka VeselaViktor StraneckyDavid KundratPavla PecherkovaJaroslav CermakAnna JonasovaMichaela Dostalova Merkerova
Published in: Cancers (2020)
we identified specific lncRNAs contributing to MDS pathogenesis and proposed cellular processes associated with these transcripts. Of the lncRNAs associated with patient prognosis, the level of H19 transcript might serve as a robust marker comparable to the clinical variables currently used for patient stratification.
Keyphrases
  • case report
  • network analysis
  • rna seq
  • long noncoding rna
  • genome wide analysis
  • breast cancer risk