Dexamethasone doses in patients with COVID-19 and hypoxia: A systematic review and meta-analysis.
Marie Warrer MunchAnders GranholmJan MalaskaJan StašekPablo O RodriguezTyler PitreRebecca WilsonJelena SavovićBram RochwergAdam SvobodnikMilan KratochvílManuel TaboadaVivekanand JhaBharath Kumar Tirupakuzhi VijayaraghavanSheila Nainan MyatraBalasubramanian VenkateshAnders PernerMorten Hylander MöllerPublished in: Acta anaesthesiologica Scandinavica (2023)
Based on low to moderate certainty evidence, higher versus standard doses of dexamethasone probably result in little to no difference in mortality, SAEs/SARs, and days alive without renal replacement therapy, but probably increase the number of days alive without invasive mechanical ventilation and circulatory support.