Brønsted Acid-Promoted Friedel-Crafts Alkylation/Cyclization of (7-Hydroxynaphthalenyl)pyrrole or (2-Hydroxyphenyl)pyrroles with Isatins for the Construction of Pyrrolospirooxindole Derivatives.
Zeng GaoJinlong ZhangHuameng YangGaoxi JiangPublished in: The Journal of organic chemistry (2018)
An efficient trifluoroacetic acid-catalyzed cascade Friedel-Crafts alkylation/cyclization of 1-(7-hydroxynaphthalenyl)pyrrole or 1-(2-hydroxyphenyl)pyrroles with isatins has been developed, providing practical access to a variety of biologically important pyrrole-containing spirooxindoles.
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