Alpha-synuclein null mutation exacerbates the phenotype of a model of Menkes disease in female mice.

MegAnne CaseyDan ZouRenee A Reijo PeraDeborah E Cabin

Published in: bioRxiv : the preprint server for biology (2023)

, encodes a copper transporter that is known to act in the trans-Golgi sub-cellular compartment. Genetic modifier effects suggest that Snca may also play a role in that compartment, potentially in the mammalian brain.

Keyphrases

white matter
resting state
genome wide
high fat diet induced
copy number
multiple sclerosis
functional connectivity
type diabetes
metabolic syndrome
adipose tissue
dna methylation
brain injury
subarachnoid hemorrhage