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A computationally efficient method for approximating reliabilities in large-scale single-step genomic prediction.

Hongding GaoAndrei A KudinovMatti TaskinenTimo J PitkänenMartin H LidauerEsa A MäntysaariIsmo Strandén
Published in: Genetics, selection, evolution : GSE (2023)
Our results demonstrate that the approximated reliabilities calculated using our proposed approach are in good agreement with the exact reliabilities. The blended method for the genotyped animals is computationally more feasible than the direct method when RPG effects are included, particularly for large-scale datasets. The approach can serve as an effective strategy to estimate the reliabilities of GEBV in large-scale single-step genomic predictions.
Keyphrases
  • copy number
  • gene expression
  • dna methylation
  • density functional theory
  • rna seq
  • molecular dynamics