Liver Injury Following Isoniazid Preventive Therapy in HIV Patients Attending Halibet National Referral Hospital, Eritrea: A Prospective Cohort Study.
Mulugeta RussomDaniel Y B JeannetotAraia Berhane MesfinHenok G WolduBruno H Ch StrickerKatia M C VerhammePublished in: Drugs - real world outcomes (2023)
DILI in PLHIV taking IPT was common; therefore, liver function should be closely monitored to safely administer the product. Despite high levels of deranged liver enzymes, the majority had no symptoms of DILI, emphasising the importance of close laboratory monitoring, especially during the first 3 months of treatment.
Keyphrases
- drug induced
- liver injury
- end stage renal disease
- antiretroviral therapy
- chronic kidney disease
- newly diagnosed
- ejection fraction
- mycobacterium tuberculosis
- prognostic factors
- healthcare
- human immunodeficiency virus
- hiv infected
- adverse drug
- hepatitis c virus
- primary care
- hiv positive
- combination therapy
- peritoneal dialysis
- electronic health record
- hiv testing
- cell therapy
- replacement therapy