Novel genomic variants related to visceral adiposity index (VAI) and body adiposity index (BAI) in Indian sib-pairs.

Tripti AgarwalTanica LyngdohRajesh KhadgawatFrank DudbridgeSanjay KinraCaroline L Relton George Davey SmithShah EbrahimDorairaj PrabhakaranGiriraj Ratan ChandakVipin GuptaGagandeep Kaur Walia

Published in: International journal of obesity (2005) (2024)

We report three novel genetic loci for VAI, and BAI in Indians that are important indicators of adiposity. These findings need to be replicated and validated with larger samples from different ethnicities. Further, functional studies for understanding the biological mechanisms of these adiposity indices need to be undertaken to understand the underlying pathophysiology.

Keyphrases

insulin resistance
copy number
weight gain
genome wide
adipose tissue
skeletal muscle
type diabetes
dna methylation
body mass index
weight loss