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Novel genomic variants related to visceral adiposity index (VAI) and body adiposity index (BAI) in Indian sib-pairs.

Tripti AgarwalTanica LyngdohRajesh KhadgawatFrank DudbridgeSanjay KinraCaroline L ReltonGeorge Davey SmithShah EbrahimDorairaj PrabhakaranGiriraj Ratan ChandakVipin GuptaGagandeep Kaur Walia
Published in: International journal of obesity (2005) (2024)
We report three novel genetic loci for VAI, and BAI in Indians that are important indicators of adiposity. These findings need to be replicated and validated with larger samples from different ethnicities. Further, functional studies for understanding the biological mechanisms of these adiposity indices need to be undertaken to understand the underlying pathophysiology.
Keyphrases
  • insulin resistance
  • copy number
  • weight gain
  • genome wide
  • adipose tissue
  • skeletal muscle
  • type diabetes
  • dna methylation
  • body mass index
  • weight loss