Epigenetic DNA methylation of Zbtb7b regulates the population of double-positive CD4 + CD8 + T cells in ulcerative colitis.

Hao-Ming XuJing XuMei-Feng YangYu-Jie LiangQuan-Zhou PengYuan ZhangCheng-Mei TianYu-Qiang NieLi-Sheng WangJun YaoDe-Feng Li

Published in: Journal of translational medicine (2022)

T cells, resulting in the production of inflammatory cytokines and colonic inflammation in UC. Therefore, Zbtb7b might be a diagnostic and therapeutic biomarker for UC, and hypo-methylation might affect the biological function of Zbtb7b.

Keyphrases

dna methylation
ulcerative colitis
genome wide
gene expression
oxidative stress