Construction and Application of a PD-L1-Targeted Multimodal Diagnostic and Dual-Functional Theranostics Nanoprobe.
Chengxue HeYanHui GuoNina ZhouZhen WangTeli LiuXiaoxia XuFeng WangHua ZhuZhi YangXianteng YangLei XiaPublished in: International journal of nanomedicine (2024)
We developed and applied a novel -targeted multimodal theranostic nanoprobe, characterized by its high specificity and superior imaging capabilities as demonstrated in PET/MRI modalities. Furthermore, this nanoprobe facilitates potent therapeutic efficacy at lower radionuclide doses when used in conjunction with PTT.
Keyphrases
- living cells
- cancer therapy
- pain management
- high resolution
- magnetic resonance imaging
- computed tomography
- photodynamic therapy
- fluorescent probe
- fluorescence imaging
- contrast enhanced
- positron emission tomography
- drug delivery
- magnetic resonance
- single molecule
- diffusion weighted imaging
- pet imaging
- chronic pain
- structural basis