Doxorubicin Exposure and Breast Cancer Risk in Survivors of Adolescent and Adult Hodgkin Lymphoma.
Suzanne I M NeppelenbroekYvonne M GeurtsBerthe M P AlemanPieternella J LugtenburgSaskia E RademakersRoel J de WeijerMaaike G A SchippersBastiaan D P TaWouter J PlattelJosée J M Zijlstra-BaalbergenRichard W M van der MaazenMarten R NijzielFrancisca OngErik C SchimmelEduardus F M PosthumaMarie José KerstenLara H BöhmerKarin MullerHarry R KoeneLiane C J Te BoomeYavuz M BilginEva de JonghCécile P M JanusFlora E van LeeuwenMichael SchaapveldPublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2024)
This study shows that treatment with doxorubicin is associated with increased BC risk in both adolescent and adult HL survivors. Our results have implications for BC surveillance guidelines for HL survivors and treatment strategies for patients with newly diagnosed HL.