Identification of bacterial lipopeptides as key players in IBS.
Camille PetitfilsSarah MaurelGaelle PayrosAmandine HueberBahija AgaizGéraldine GazzoRémi MarroccoFrédéric AuvrayGeoffrey LangevinJean-Paul MottaPauline FlochMarie Tremblay-FrancoJean-Marie GalanoAlexandre GuyThierry DurandSimon LachambreAnaëlle DurbecHind HusseinLisse DecraeckerJustine Bertrand-MichelAbdelhadi SaoudiEric OswaldPierrick PoisbeauGilles DietrichChloe MelchiorGuy E BoeckxstaensMatteo SerinoPauline Le FaouderNicolas CenacPublished in: Gut (2022)
PS impacts the gut microbiota composition and metabolic function in adulthood. The reduced capacity of the gut microbiota to produce GABA lipopeptides could be one of the mechanisms linking PS and visceral hypersensitivity in adulthood.