Honokiol attenuates lipotoxicity in hepatocytes via activating SIRT3-AMPK mediated lipophagy.
Jingxin LiuTian ZhangJianzhong ZhuShuangchen RuanRongsong LiBing GuoLi-Gen LinPublished in: Chinese medicine (2021)
These results suggest that HK could ameliorate lipotoxicity in hepatocytes by activating SIRT3-AMPK-lipophagy axis, which might be a potential therapeutic agent against NAFLD.