Increased Transfection of the Easily Oxidizable GC-Rich DNA Fragments into the MCF7 Breast Cancer Cell.
Svetlana V KostyukNadezhda N MordkovichNatalya A OkorokovaVladimir P VeikoElena M MalinovskayaElizaveta S ErshovaMarina S KonkovaEkaterina A SavinovaMaria A BorzikovaTatiana A MuzaffarovaLev N PorokhovnikNataly N VeikoSerguey I KutsevPublished in: Oxidative medicine and cellular longevity (2019)
GC-rich cfDNA fragments that are prone to oxidation can easily penetrate the cancer cells and be expressed. The cfDNA should become a target for the antitumor therapy.