Transcriptome- and proteome-wide association studies nominate determinants of kidney function and damage.

Pascal SchlosserJingning ZhangHongbo LiuAditya L SurapaneniEugene P RheeDan E ArkingBing YuEric BoerwinklePaul A WellingNilanjan ChatterjeeKatalin SusztakJosef CoreshMorgan E Grams

Published in: Genome biology (2023)

In summary, this study combines multimodal, genome-wide association studies to generate a catalog of putatively causal target genes and proteins relevant to kidney function and damage which can guide follow-up studies in physiology, basic science, and clinical medicine.

Keyphrases

case control
genome wide association
oxidative stress
genome wide
gene expression
dna methylation
rna seq
pain management
transcription factor
genome wide analysis