Influence of CYP3A5 and ABCB1 polymorphisms on the pharmacokinetics of vincristine in adult patients receiving CHOP therapy.

Junichi NakagawaTakenori TakahataYu ChenKensuke SaitoKosuke KamataTakuto TachitaSatoru YamashitaKeigo SaitoKayo UenoAtsushi SatoHirotake SakurabaTakenori Niioka

Published in: Cancer chemotherapy and pharmacology (2023)

The CYP3A5*3 polymorphism was found to be an indicator for predicting exposure to VCR in adult patients receiving CHOP therapy. This information may be useful for the individualization of VCR dosages.

Keyphrases

diffuse large b cell lymphoma
stem cells
childhood cancer
mesenchymal stem cells
social media
cell therapy
chemotherapy induced