Prodromal Spinocerebellar Ataxia Type 2 Subjects Have Quantifiable Gait and Postural Sway Deficits.
Velázquez-Pérez LuisRoberto Rodriguez-LabradaYasmani González-GarcésEduardo Arrufat-PieReidenis Torres-VegaJacqueline Medrano-MonteroBeatriz Ramirez-BautistaYaimeé Vazquez-MojenaGeorg AuburgerFay HorakUlf ZiemannChristopher M GomezPublished in: Movement disorders : official journal of the Movement Disorder Society (2020)
This study demonstrates early alteration of gait and postural sway control in prodromal SCA2 using a wearable sensor-based system. This offers new pathophysiological hints into this early disease stage and provides novel potential biomarkers for future clinical trials. © 2020 International Parkinson and Movement Disorder Society.