The accuracy and intra- and interobserver variability of PSMA PET/CT for the local staging of primary prostate cancer.
Maarten L DonswijkRosemarijn H EttemaDennie MeijerMaurits WondergemZing CheungElise M BekersPim J van LeeuwenRoderick C N van den BerghHenk G van der PoelAndré N VisDaniela E Oprea-LagerPublished in: European journal of nuclear medicine and molecular imaging (2024)
In a large, multicentre study evaluating 600 patients with newly diagnosed intermediate and high-risk PCa, we showed that PSMA PET/CT may have a value in local tumour staging when pathological tumour stage in the radical prostatectomy specimen was used as the reference standard. The intra-observer and interobserver variability of assessment of tumour extent on PSMA PET/CT was moderate to substantial.