Population Pharmacokinetic Model of N-acetylmannosamine (ManNAc) and N-acetylneuraminic acid (Neu5Ac) in Subjects with GNE Myopathy.

Scott Van WartDonald E MagerCindy J BednaszMarjan Huizing Nuria Carrillo-Carrasco

Published in: Drugs in R&D (2021)

This population pharmacokinetic model can be used to evaluate ManNAc dosing regimens and to calculate Neu5Ac production and exposure following oral administration of ManNAc in subjects with GNE myopathy.

Keyphrases

late onset