Cell-free DNA analysis for recurrent respiratory papillomatosis: A case report.
Satoshi YamadaKotaro KanoRyuji IshikawaAtsushi ImaiDaiki MochizukiKotaro MoritaKazutaka TakeuchiYoshinori TakizawaHideya KawasakiKiyoshi MisawaPublished in: Clinical case reports (2024)
A 35-year-old male presented with recurrent respiratory papillomatosis. Human papillomavirus type 11 was detected from all sites of tumor tissue DNA by PCR. The pre-surgery cell-free DNA (cfDNA) viral load (3.33 × 10 3 copies/ng DNA) fell below the post-surgical detection limits on achieving remission, suggesting cfDNA's potential as a biomarker.
Keyphrases
- circulating tumor
- cell free
- single molecule
- minimally invasive
- real time pcr
- coronary artery bypass
- nucleic acid
- disease activity
- circulating tumor cells
- loop mediated isothermal amplification
- surgical site infection
- human health
- systemic lupus erythematosus
- ulcerative colitis
- risk assessment
- atrial fibrillation
- climate change
- sensitive detection