High Prevalence of Tuberculosis Infection and Disease in Child Household Contacts of Adults With Rifampin-resistant Tuberculosis.
Soyeon KimXingye WuMichael D HughesCaryn M UptonKim NarunskyAlberto Mendoza-TiconaSaltnat KhajenooriPedro GonzalesSharlaa Badal-FaesenJustin ShenjeAyotunde Omoz-OarheVanessa RouzierAnthony J Garcia-PratsAnne-Marie DemersLinda NainiElizabeth SmithGavin ChurchyardSusan SwindellsN Sarita ShahAmita GuptaAnneke C Hesselingnull nullPublished in: The Pediatric infectious disease journal (2022)
The prevalence of TB infection and disease was high in child HHC exposed to rifampin-resistant TB. Few children had routinely received TPT. High-quality evidence is needed to inform strong recommendations for and access to TPT in children exposed to TB resistant to rifampin.